Are you Meeting the European Directive for Dosimetry?

Are you Meeting the EANM Directive for Dosimetry?

Council Directive 2013/59/Euratom1 specifies the need to verify delivered doses from radiation treatments and outlines clinician, and patient safety as top priorities.

Absorbed doses should be calculated and reported for individual patients. However, not all dosimetry systems are created equal in this regard. Model-based systems were designed for population-based dosimetry as opposed to individual patient dosimetry. These systems use a standard anatomy to calculate the dose, as assumptions are made about the patient’s size, which does not account for dose from tumors in the body.

In order to calculate absorbed doses to individual patients, a patient-specific approach is needed that uses the patient’s own unique anatomy and burden of tumors.

Not all dosimetry systems are created equal

1. European Society of Radiology (ESR). Summary of the European Directive 2013/59/Euratom: essentials for health professionals in radiology. Insights Imaging. 2015;6(4):411–417. doi:10.1007/s13244-015-0410-4

Are you Prepared to Deliver More Dose?

Personalized therapies cater to patients based on their unique anatomy, tumor load, and physiology. Why settle for generic, model-based approaches when you could use the patient's own images? Studies have shown2 that with patient-specific dosimetry, more dose can be delivered to most patients3 without overdosing normal tissues such as the kidneys.

Deliver More Tumor Dose

Today, regardless of the patient, dosage for Lu-177 dotatate is often underdosed in support of safety, which may be under-treating many of the tumors. This means the actual absorbed doses are variable between patients and often, the tumors receive lower than necessary doses while still keeping normal organ doses within safety targets. Are you prepared to deliver more tumor dose?

Evaluate Normal Structure Dose

Ensuring accuracy in dose delivery to a tumor load without affecting nearby normal structures is critical in dosimetry. Are you prepared to evaluate the dose to normal structures?

Provide Key Treatment Information to Referrers

Reports with statistics and images are essential in communicating valuable treatment course information to referrers. Are you prepared to provide key treatment information to referring physicians?

2. Mattias Sandström, Ulrike Garske-Román, Dan Granberg, Silvia Johansson, Charles Widström, Barbro Eriksson, Anders Sundin, Hans Lundqvist and Mark Lubberink. Individualized Dosimetry of Kidney and Bone Marrow in Patients Undergoing 177Lu-DOTA-Octreotate Treatment. J Nucl Med. 2013 Jan;54(1):33-41. Epub 2012 Dec 7.

3. Del Prete M, Buteau FA, Arsenault F, Saighi N, Bouchard LO, Beaulieu A, Beauregard JM. Personalized 177Lu-octreotate peptide receptor radionuclide therapy of neuroendocrine tumours: initial results from the P-PRRT trial. Eur J Nucl Med Mol Imaging. 2019 Mar;46(3):728-742.  Epub 2018 Nov 30.

Delivering a Personalized Approach

MIM provides valuable tools that help to offset the clinical time burden often associated with dosimetry for every step of the Nuclear Medicine workflow.

MIM’s roots in Radiation Oncology provide valuable expertise and robust, automated tools that result in accuracy and timesavings for image segmentation, dosimetry, and reporting. How are you preparing to deliver a personalized treatment for your patients?

MIM SurePlan MRT™*

Advancing Molecular Radiotherapy

MIM SurePlan LiverY90™

A Comprehensive Solution for Y90

MIM SurePlan MRT™*

Advancing Molecular Radiotherapy

Knowing the patient-specific dose doesn’t need to add significant time to your workflow. MIM SurePlan MRT provides effective dosimetry, organ and tumor segmentation, deformable registration, and communication tools that help reduce clinical effort — in a single solution.

Timesaving Tools

Automated segmentation can significantly reduce the time required to generate organ volumes such as the kidneys and liver. Industry-leading PET and SPECT segmentation tools are available for tumors and other volumes of interest (VOI).

Multi-Tracer Theranostics Support

Multiple molecular radiotherapy tracers such as Lutathera Lu-177 dotatate, Azedra I-131 iobenguane, Hicon I-131 NAI for thyroid, and more can be imaged with MIM SurePlan MRT, providing confirmation of dose delivery in the patient.

Quantitative SPECT and Planar Corrections

Vendor-neutral quantitative SPECT reconstruction is available for dosimetry in SPECTRA Quant™. Now, clinicians can generate quantitative images off of the imaging so that dose can be measured as opposed to measuring the amount of activity.

Multi-Modality Compatibility

Compare PET, SPECT, CT, MRI, and CBCT within MIM’s intuitive interface. Multi-modality rigid and deformable fusion ensure consistency when there are differences in position, size, and organ movement.

Voxel-Based Dosimetry

SurePlan MRT provides voxel-based absorbed dose calculation using the patient’s own anatomy. Calculate isodose curves/DVH on SPECT using voxel s-value scheme in MIRD Pamphlet No.17. MIM’s automated tools for serial exam comparison make therapy response evaluation viable.

Improve Communication with Referrers

Supply more dosimetric information to referring physicians using the integrated reporting solution with images and statistics.Dictated text can be pulled into reports from PowerScribe® 360 and exported to PDF or DICOM structured reports.

* CE pending. May not yet be commercially available in some countries. Please contact your local MIM rep for further details.

MIM SurePlan LiverY90™

A Comprehensive Solution for Y90

Timesaving tools for organ and tumor segmentation, deformable registration, and voxel-based dosimetry for molecular radiotherapy.

Timesaving Tools

MIM SurePlan LiverY90 is specifically engineered for Y90, making efficiency a top priority. A recent study4 in the Journal of Nuclear Medicine demonstrated a 70% reduction in time compared to manual outlining of the liver.

Lobe and Liver Segmentation

Segment the lobe and liver with Atlas-based segmentation and Contour CoPilot™.

Post-Op Dosimetry

Calculate dose using Y90-PET and Bremsstrahlung SPECT. Calculate isodose curves/DVH on PET/SPECT using Local Disposition Method or MIRD Kernal.

4. M Horvat B.S., M.S, AS Nelson, M.D., SD Pirozzi, B.S. Time Savings of a Multi-Atlas Approach for Liver Segmentation. J Nucl Med May 2014 vol. 55 no. supplement 1 1523.


Download the study, Time Savings of a Multi-Atlas Approach for Liver Segmentation.


Standardize your Workflow

MIM’s flexible user interface allows you to customize reading workflows to the preference of the department and optimize the clinical workflow. Integrate MIM into the existing hospital PACS or with PowerScribe® 360 for a truly seamless experience.

Data Management

How Are you Preparing for the Future?

Storing dosimetry data as well as tumor and organ segmentations for future analysis is an essential move toward improving therapeutic outcomes for all structured data.

As the demand for clinical efficiency grows, data management becomes an essential component for maintaining effective care. MIM provides solutions that make it easy to extract meaningful information from all imaging data collected in the Nuclear Medicine department.

More Nuclear Medicine Solutions

MIM offers other Nuclear Medicine solutions beyond dosimetry.

MIM Encore®

A Comprehensive Solution for PET and Nuclear Medicine

Combine industry-leading therapy response tools for PET with advanced Nuclear Medicine display and processing.

MIMneuro®

Visualize the Difference in Brain Analysis

With our quantitative analysis software at work, we make it easy for you to review your exams and gather your results. Experience multi-tracer support and quick quantitative analysis all at your fingertips. Learn more about the features and see how you can visualize the difference with MIMneuro.

MIMcardiac®

Quantitative Analysis for Cardiac PET and SPECT

Stress less and rest more with MIMcardiac at your fingertips. We've designed our cardiac software to fit your needs with quick and effective quantitative analysis in one solution. Experience cardiac software innovation at its best with our robust image registration, automated left ventricle segmentation, and more. Put MIMcardiac at the heart of your routine.